Photo Highway = a main road, especially one connecting major towns or cities. Interstate = one of a system of expressways covering the 48 contiguous states. Spotlight: Highways and Interstates in the USA Interstate 10 Interstate 11 Interstate 35 Interstate 40 Interstate 70 Interstate 80 Route 66 Elsewhere on the web https://www.cnu.org/our-projects/highways-boulevards/freeways-without-futures Planeta.com Travel